| Rank | Student | Grade | School | Year | | G | Pts |
| 1 | Melissa Grider | Jr | Marion C. Early | 1989-1990 | 1989-1990 | 29 | 1231 |
| 2 | Hannah Wilkerson | Sr | Miller | 2009-2010 | 2009-2010 | 32 | 1215 |
| 3 | Sierra Michaelis | Sr | Mercer | 2012-2013 | | 31 | 1075 |
| 4 | Leah Cauble | Sr | Oran | 2018-2019 | | 29 | 1059 |
| 5 | Leah Cauble | So | Oran | 2016-2017 | 2016-2017 | 32 | 1058 |
| 6 | Joyce Amsmeyer | Sr | Southern Boone | 1965-1966 | 1965-66 | 25 | 994 |
| 7 | Brook Littrell | Sr | Green City | 2019-2020 | | 29 | 986 |
| 8 | Leah Cauble | Jr | Oran | 2017-2018 | | 29 | 982 |
| 9 | Lacey Clark | Sr | Belle | 2014-2015 | 2014-2015 | 25 | 973 |
| 10 | Sierra Michaelis | Jr | Mercer | 2011-2012 | 2011-2012 | 29 | 969 |
| 11 | Cady Pauley | Sr | Milan | 2021-2022 | | 29 | 957 |
| 12 | Kari Koch | Sr | Elsberry | 2001-2002 | 2001-2002 | 32 | 956 |
| 13 | Shyla Tucker | Jr | Fredericktown | 1988-1989 | 1988-1989 | 27 | 952 |
| 13 | Hannah Wilkerson | Jr | Miller | 2008-2009 | 2008-2009 | 30 | 952 |
| 15 | Jessica Keller | Sr | Belle | 2004-2005 | | 25 | 938 |
| 16 | Kaylee King | Sr | Ellington | 2022-2023 | | 28 | 910 |
| 17 | Kenna Allan | Sr | Gilman City | 1966-1967 | | 24 | 897 |
| 18 | Brooke Littrell | Jr | Green City | 2018-2019 | | 29 | 896 |
| 19 | Cassidy Hambelton | Sr | Dora | 2021-2022 | | 29 | 892 |
| 20 | Brandi Jackson | Jr | Kennett | 1996-1997 | | 20 | 862 |
| 21 | Lacy Stokes | Sr | Mt. Vernon | 2020-2021 | | 32 | 825 |
| 22 | Cady Pauley | Jr | Milan | 2020-2021 | | 26 | 810 |
| 22 | Ashton Bailey Judd | Sr | West Plains | 2021-2022 | | 31 | 810 |
| 24 | Reagan Wobbe | Sr | St. Elizabeth | 2025-2026 | | 32 | 799 |
| 25 | Jamiah Renee Herring-Green | So | Hazelwood West | 2025-2026 | | 26 | 789 |
| 26 | Kaylee King | Jr | Ellington | 2021-2022 | | 30 | 788 |
| 27 | Ida McHarg | Sr | Blue Springs | 1950-1951 | | 19 | 761 |
| 27 | Gertrude Fowler | Sr | Osborn | 1958-1959 | | 23 | 761 |
| 29 | Kaylee King | So | Ellington | 2020-2021 | | 28 | 760 |
| 30 | Abby Backes | Sr | Tipton | 2019-2020 | | 32 | 753 |
| 31 | Myra Claas | Sr | Tipton | 2022-2023 | | 32 | 740 |
| 32 | Madison Nelson | Sr | Kingston | 2021-2022 | | 25 | 732 |
| 33 | Cady Pauley | So | Milan | 2019-2020 | | 25 | 718 |
| 34 | Karen Thies | Sr | Osceola | 1978-1979 | | 19 | 710 |
| 35 | Madison Nelson | So | Kingston | 2019-2020 | | 26 | 699 |
| 35 | Sophia Hancock | Sr | Puxico | 2019-2020 | | 26 | 699 |
| 37 | Korrie Holcer | Sr | Meadville | 2023-2024 | | 29 | 697 |
| 38 | Madison Nelson | Jr | Kingston | 2020-2021 | | 22 | 676 |
| 39 | Gracee Smith | Jr | Arcadia Valley | 2019-2020 | | 27 | 672 |
| 40 | | Jr | Drexel | 2021-2022 | | 29 | 670 |
| 40 | Emily Wheeler | Jr | Drexel | 2021-2022 | | 29 | 670 |
| 42 | Abby Backes | So | Tipton | 2017-2018 | | 30 | 665 |
| 42 | Cassidy Hambelton | Jr | Dora | 2020-2021 | | 26 | 665 |
| 44 | Serena Sundell | Jr | Maryville | 2019-2020 | | 27 | 651 |
| 44 | Lilyan Carr | So | Spokane | 2024-2025 | | 27 | 651 |
| 46 | Abby Backes | Jr | Tipton | 2018-2019 | | 29 | 643 |
| 47 | India Willis | So | Macks Creek | 2022-2023 | | 30 | 641 |
| 48 | Anna Parker | Sr | South Iron | 2023-2024 | | 28 | 640 |
| 49 | India Willis | Fr | Macks Creek | 2021-2022 | | 26 | 638 |
| 50 | Madison Carvajal | So | Meadville | 2023-2024 | | 29 | 636 |
| 50 | Madison Carvajal | So | Tipton | 2023-2024 | | 29 | 636 |
| 52 | Ava Schlotzhauer | Jr | Tipton | 2024-2025 | | 32 | 629 |
| 53 | Ava Schlotzhauer | So | Tipton | 2023-2024 | | 32 | 604 |
| 54 | Emily Wheeler | So | Drexel | 2020-2021 | | 24 | 601 |
| 55 | Chloe Jones | So | Willow Springs | 2023-2024 | | 28 | 599 |
| 56 | Cassidy Hambelton | So | Dora | 2019-2020 | | 25 | 596 |
| 57 | Myra Claas | So | Tipton | 2020-2021 | | 30 | 591 |
| 58 | Madison Carvajal | Sr | Tipton | 2025-2026 | | 32 | 590 |
| 58 | Ava Schlotzhauer | Sr | Tipton | 2025-2026 | | 32 | 590 |
| 60 | Cady Pauley | Fr | Milan | 2018-2019 | | 24 | 589 |
| 61 | Madison Carvajal | Fr | Tipton | 2022-2023 | | 29 | 581 |
| 62 | Mallory Moss | So | Richland | 2024-2025 | | 29 | 574 |
| 63 | Chloe Bukowsky | Sr | Southern Boone | 2023-2024 | | 27 | 560 |
| 64 | Jacie Jo Kassanavoid | So | Lathrop | 2024-2025 | | 28 | 549 |
| 65 | Kayla Hamilton | Fr | Hollister | 2024-2025 | | 27 | 513 |
| 66 | Isabel Maddick | Jr | Lathrop | 2013-2014 | | 28 | 495 |
| 67 | Janelle Saling | Sr | Lathrop | 2010-2011 | | 26 | 478 |
| 68 | Isabel Maddick | Sr | Lathrop | 2014-2015 | | 26 | 458 |
| 69 | Kaitlyn P Morgan | Sr | Lathrop | 2023-2024 | | 28 | 450 |
| 70 | Katie Cordray | Sr | Lathrop | 2013-2014 | | 28 | 436 |
| 71 | Isabel Maddick | So | Lathrop | 2012-2013 | | 25 | 429 |
| 72 | Brenna Couch | Sr | Plato | 2023-2024 | | 22 | 421 |
| 73 | Jacie Jo Kassanavoid | Fr | Lathrop | 2023-2024 | | 28 | 414 |
| 73 | Kinzie Pettijohn | Sr | Union Star | 2025-2026 | | 27 | 414 |
| 75 | Cady Pauley | Fr | Milan | 2018-2019 | | 24 | 245 |