| Rank | Total | Student | School | Opponent | Date | |
| 1 | 50 | | Central (St. Louis) | Vashon | 2/1/1980 | |
| 2 | 48 | | Van-Far | Mexico | 1/24/1970 | |
| 3 | 47 | | Mercer | Braymer | 1/30/2003 | at Meadville |
| 4 | 45 | | Southern Boone | Sturgeon | 2/26/1999 | |
| 5 | 44 | | Notre Dame (Cape Girardeau) | Sikeston | 11/30/1982 | |
| 5 | 44 | | Ballard | Heartland Academy | 1/10/2008 | |
| 7 | 43 | | New Franklin | Keytesville | 2/7/1978 | |
| 7 | 43 | | Vashon | Lincoln College Prep | 3/1/1985 | |
| 7 | 43 | | Troy Buchanan | Winfield | 1/22/1987 | |
| 7 | 43 | | North Harrison | Harrisburg | 3/12/1988 | at MSU |
| 7 | 43 | | North Harrison | Harrisburg | 3/1/1988 | |
| 7 | 43 | | Vashon | Lincoln College Prep | 3/8/1995 | at UMC |
| 7 | 43 | | East Carter | Couch | 1/13/2012 | |
| 14 | 37 | | Raytown South | Sumner | 3/1/1972 | |
| 15 | 36 | | Whitfield | Hogan Prep Academy Charter | 3/1/2017 | |
| 16 | 33 | | Fordland | Bishop Hogan High | 3/1/1998 | |
| 17 | 32 | | Central (KC) | Troy Buchanan | 3/1/1999 | |
| 17 | 32 | | St. Elizabeth | Bell City | 3/1/2005 | |