| Rank | Total | Student | School | Opponent | Date | |
| 1 | 151 | | Lebanon | Lebanon | 5/18/2023 | |
| 2 | 9 | Jayden Hasam | University Academy Charter | Southeast | 3/28/2022 | |
| 3 | 8 | Darryl Williams | Lincoln College Prep | Northeast (Kansas City) | 4/26/2018 | |
| 4 | 7 | David Miller | Belle | Cuba | 4/12/1983 | |
| 4 | 7 | Kenny McKinley | Hume | Bronaugh | 10/10/1995 | |
| 4 | 7 | Danny Maier | New Franklin | Harrisburg | 4/16/2004 | |
| 4 | 7 | Matt Collins | Dora | Couch | 4/8/2005 | |
| 4 | 7 | Dusty Smith | Dora | Couch | 4/8/2005 | |
| 4 | 7 | Lee Allen, Jr. | Lincoln College Prep | Southeast | 3/23/2018 | |
| 4 | 7 | Logan Primanzon | Cabool | | 3/28/2019 | |
| 4 | 7 | Jayden Hasam | University Academy Charter | Washington ( Kansas City, KS) | 3/30/2021 | |
| 12 | 6 | Gary Spradling | Central (Cape Girardeau) | Immaculate Conception (Jackson) | 3/19/1961 | |
| 12 | 6 | David Miller | Belle | Vienna | 4/7/1983 | |
| 12 | 6 | Craig Casey | Hume | Ballard | 5/2/1990 | |
| 12 | 6 | Brent Morrison | Hume | Ballard | 5/2/1990 | |
| 12 | 6 | Kimo Concepcion | Stoutland | Climax Springs | 3/26/1999 | |
| 12 | 6 | Kimo Concepcion | Stoutland | Laquey | 8/31/1999 | |
| 12 | 6 | Justin Coliny | Wright City | Silex | 4/17/2002 | |
| 12 | 6 | Jason Hayes | Lawson | East Buchanan | 4/28/2005 | |
| 12 | 6 | James Gowin | Hermitage | Weaubleau | 4/24/2008 | |
| 12 | 6 | James Gowin | Hermitage | Macks Creek | 5/1/2008 | |
| 12 | 6 | Shawn Burkhardt | Hermitage | Climax Springs | 4/20/2009 | |
| 12 | 6 | Jared Patrick Mcelfresh | DeKalb | University Academy Charter | 4/19/2018 | |
| 12 | 6 | Colby Phillips | Southern Boone | | 3/16/2019 | v.s Fulton |
| 12 | 6 | Graham Todd | Plato | Newburg | 4/13/2021 | |
| 12 | 6 | Wyatte Cotrel | Plato | Newburg | 4/13/2021 | |
| 27 | 5 | Ethan Caddell | Exeter | | 5/7/2018 | |
| 27 | 5 | Jared Alverson | Exeter | | 4/23/2018 | |
| 27 | 5 | Devrin Weathers | Webb City | Neosho | 5/4/2021 | |
| 27 | 5 | McCade Dixon | Winona | Van Buren | 4/12/2021 | |
| 27 | 5 | Joshua Prisco | Summersville | Koshkonong | 9/27/2022 | |
| 27 | 5 | Kasen Gaston | Summersville | Newburg | 5/1/2023 | |
| 27 | 5 | Reece Eftink | Kelly | Central (New Madrid County) | 4/4/2024 | |
| 34 | 4 | Randy Cayce | Crystal City | Southwest (STL) | 5/29/1965 | |
| 34 | 4 | Billy Loper | Oran | Halfway | 6/5/1998 | |
| 34 | 4 | Richard Wright | Pembroke Hill | Logan-Rogersville | 6/5/2011 | |
| 34 | 4 | McCade Dixon | Winona | Dora | 5/6/2021 | |
| 34 | 4 | McCade Dixon | Winona | Bunker | 4/6/2021 | |