| Rank | Student | School | Opponent | Date | | Inn | Total |
| 1 | | Central (Cape Girardeau) | Notre Dame (Cape Girardeau) | 4/8/1960 | | | 5 |
| 1 | | Ft. Zumwalt West | Ft. Zumwalt West | 3/31/2012 | | 7 | 5 |
| 1 | | Ft. Zumwalt West | Lafayette (Wildwood) | 3/31/2012 | | 7 | 5 |
| 1 | | Southern Boone | Arkansas City, KS | 4/16/2022 | | 6 | 5 |
| 5 | | Westran | Neelyville | 5/31/1989 | at UMC | | 4 |
| 5 | | Holcomb | Halfway | 6/5/1997 | at UMC | | 4 |
| 5 | | Holcomb | Halfway | 6/5/1997 | | 7 | 4 |
| 5 | | Liberty | Lebanon | 5/31/2002 | at UMC | 6 | 4 |
| 5 | | Liberty | Lebanon | 5/31/2002 | | 7 | 4 |
| 5 | | Lawson | Lathrop | 4/26/2005 | | | 4 |
| 5 | | Central (Cape Girardeau) | Scott City | 5/13/2005 | | | 4 |
| 5 | | Walnut Grove | Clever | 4/22/2006 | | | 4 |
| 5 | | Union | North County | 4/7/2010 | | | 4 |
| 14 | | Oak Park | Lafayette (Wildwood) | 6/6/1987 | at UMC | | 3 |
| 14 | | Bismarck | Westran | 6/1/1989 | at UMC | | 3 |
| 14 | | Mansfield | St. Pius X (Kansas City) | 5/30/1991 | at UMC | | 3 |
| 14 | | Fatima | Ash Grove | 6/4/1992 | at UMC | | 3 |
| 14 | | Parkway North | Ft. Zumwalt West | 4/12/2003 | | 7 | 3 |
| 14 | | Walnut Grove | Humansville | 5/6/2004 | | | 3 |
| 14 | | Oran | Bevier | 6/2/2004 | at UMC | | 3 |
| 14 | | Mansfield | Ash Grove | 4/1/2006 | at Willard | 5 | 3 |
| 14 | | Monett | Seneca | 4/9/2009 | | | 3 |
| 14 | | Parkway North | University City | 4/19/2010 | | 7 | 3 |
| 14 | | Parkway North | St. Charles | 3/23/2013 | | 5 | 3 |
| 14 | | Parkway North | Ft. Zumwalt North | 4/10/2014 | | 7 | 3 |
| 14 | | Parkway North | Kirkwood | 4/17/2017 | | 7 | 3 |