| Rank | Student | School | Years | | G | R |
| 1 | Maleigh Elizabeth Lemings | Holcomb | 2020-2023 | | 127 | 243 |
| 2 | Paige Eddington | Doniphan | 2014-2017 | | 134 | 225 |
| 3 | Madison Marie Uptegrove | Father Tolton Regional Catholic | 2020-2023 | | 131 | 188 |
| 4 | Molly Daniels | Mt. Vernon | 2021-2024 | | 139 | 180 |
| 5 | Macie Botsch | Bernie | 2021-2024 | | 126 | 177 |
| 6 | Payge Evans | Mt. Vernon | 2020-2023 | | 128 | 175 |
| 7 | Emily Crane | Troy Buchanan | 2008-2011 | | 118 | 168 |
| 7 | Abi Chipps | Jefferson (Festus) | 2016-2019 | | 99 | 168 |
| 9 | Sammey Clara Bunch | Fatima | 2012-2015 | | 108 | 167 |
| 10 | Regan Nash | North Platte | 2011-2014 | | 94 | 164 |
| 10 | Mallory Ann Gazaway | Liberal | 2015-2018 | | 102 | 164 |
| 10 | Abigail Kriete | Rolla | 2022-2025 | | 123 | 164 |
| 13 | Cali Coombs | Russellville | 2019-2022 | | 115 | 163 |
| 14 | Sarah Roth | Northwest (Cedar Hill) | 2017-2020 | | 113 | 160 |
| 14 | Hailey Presley | Marion C. Early | 2020-2023 | | 123 | 160 |
| 14 | Jordan Goodell | Liberal | 2021-2024 | | 112 | 160 |
| 17 | Karsyn Brooke | Mansfield | 2015-2018 | | 132 | 159 |
| 18 | Maddison Brown | Mt. Vernon | 2013-2016 | | 100 | 158 |
| 18 | Livia Dumm | Jasper | 2021-2023 | | 114 | 158 |
| 20 | Ragan Blinzler | Pierce City | 2014-2017 | | 99 | 156 |
| 20 | Lauren Taylor | Marion C. Early | 2019-2022 | | 96 | 156 |
| 20 | Autumn Diane Kinnaird | Neosho | 2022-2025 | | 132 | 156 |
| 23 | Zoe Brittan | Valley Park | 2004-2006 | | 74 | 154 |
| 24 | Bailey Burns | Puxico | 2015-2018 | | 80 | 153 |
| 25 | Tabitha Francka | Marion C. Early | 2012-2015 | | 95 | 152 |
| 26 | Kloee Williamson | McAuley Catholic | 2020-2023 | | 88 | 151 |
| 27 | Sydney Miller | Willow Springs | 2015-2018 | | 105 | 150 |
| 27 | Sophia Luetticke | Chillicothe | 2018-2021 | | 94 | 150 |
| 29 | Olivia Jo Pfeifer | Hannibal | 2014-2017 | | 95 | 148 |
| 30 | Reece Gabrielle Barnett | Macon | 2022-2025 | | 129 | 147 |
| 31 | Valerie Teter | Bevier | 2003-2006 | | 99 | 146 |
| 32 | Alane Cordray | Mt. Vernon | 2014-2017 | | 84 | 144 |
| 33 | Kelli Koehler | Weaubleau | 2009-2012 | | 109 | 143 |
| 34 | Alexis Van Nostrand | Palmyra | 2009-2012 | | 124 | 141 |
| 34 | Kassidy Watts | Sparta | 2015-2018 | | 66 | 141 |
| 34 | Alexi Sanchez | Northwest (Cedar Hill) | 2018-2021 | | 106 | 141 |
| 34 | Maris Ollison | Versailles | 2018-2021 | | 103 | 141 |
| 38 | Abigail Rickermann | Festus | 2016-2019 | | 102 | 138 |
| 39 | Halle Gooch | Clearwater | 2014-2017 | | 93 | 133 |
| 40 | Audrey Glenski | North Platte | 2011-2014 | | 103 | 132 |
| 41 | Jonette Dixon | Putnam County | 1988-1991 | | 91 | 127 |
| 42 | Elle Smith | Blue Springs South | 2018-2021 | | 35 | 120 |
| 43 | Catryn Cattoor | Jefferson (Festus) | 2017-2020 | | 92 | 118 |
| 44 | Abigail King | Christian | 2014-2017 | | 84 | 116 |
| 45 | Maggie Painter | Marion C. Early | 2020-2023 | | 118 | 114 |