| Rank | Student | School | Years | | G | Total |
| 1 | Paige Eddington | Doniphan | 2014-2017 | | 134 | 484 |
| 2 | Madison Marie Uptegrove | Father Tolton Regional Catholic | 2020-2023 | | 131 | 452 |
| 3 | Maris Ollison | Versailles | 2018-2021 | | 103 | 385 |
| 4 | Addison Purvis | Sullivan | 2016-2019 | | 117 | 380 |
| 4 | Kayla Patricia Ulrich | Sullivan | 2019-2022 | | 132 | 380 |
| 6 | Nicole Hudson | Webb City | 2005-2008 | | 117 | 372 |
| 7 | Ali Raley | Pierce City | 2014-2017 | | 100 | 355 |
| 8 | Sammey Clara Bunch | Fatima | 2012-2015 | | 108 | 345 |
| 9 | Emma Nichols | Hillsboro | 2015-2018 | | 117 | 344 |
| 10 | Hannah Marie Cox | Sullivan | 2016-2019 | | 118 | 342 |
| 11 | Dana M Graves | Weaubleau | 2009-2012 | | 109 | 336 |
| 12 | Karsyn Brooke | Mansfield | 2015-2018 | | 132 | 322 |
| 13 | Kylie Marie Helm | McDonald County | 2015-2018 | | 112 | 320 |
| 14 | Ashley Ellis | Fox | 2012-2015 | | 113 | 310 |
| 15 | Makenzie Goswick | Joplin | 2012-2015 | | 120 | 307 |
| 16 | Caitlin Chapin | Ozark | 2005-2008 | | 120 | 302 |
| 16 | Molly Carter | Hickman | 2011-2014 | | 105 | 302 |
| 18 | Emily Crane | Troy Buchanan | 2008-2011 | | 118 | 298 |
| 19 | | Sullivan | 2017-2020 | | 117 | 292 |
| 20 | Valerie Teter | Bevier | 2003-2006 | | 99 | 286 |
| 21 | Alexis Van Nostrand | Palmyra | 2009-2012 | | 124 | 283 |
| 22 | Maci Moore | Trenton | 2018-2021 | | 106 | 282 |